遺伝子組換え技術を用いた牛、羊用汎用生ワクチン作出技術の開発(国立大学法人東京大学)

遺伝子組換え技術を用いた牛、羊用汎用生ワクチン作出技術の開発(国立大学法人東京大学)

課題番号2010017269
研究機関名東京大学,畜産生物科学安全研究所,共立製薬株式会社,株式会社微生物化学研究所
研究期間2009-2011
年度2010
小課題遺伝子組換え技術を用いた牛、羊用汎用生ワクチン作出技術の開発(国立大学法人東京大学)
摘要アカバネウイルス生ワクチン株を骨格とする遺伝子組換え型生ワクチン候補株の作出等
予算区分消費・安全局[レギュラトリー・サイエンス]
業績(1)Fibrinoid Leukodystrophy (Alexander’s disease-like disorder in a Young Adult French Bulldog
(2)Systemic T cell large granular lymphocyte lymphoma with multifocal white matter degeneration in the brain of a Japanese domestic cat
(3)Long term survival of primary skeletal muscle lymphoma in a Miniature Dachshund
(4)Immunohistochemical characterization of canine neuroepithelial tumors
(5)Inflammatory myopathy with severe toungue atrophy in Pembroke Welsh Corgi dogs
(6)GM2 gangliosidosis variant 0 (Sandhoff-like disease) in a family of toy poodles
(7)Neuroblastoma of the adrenal gland in a ferret
(8)Hemangioma of the Ileum in a Dog
(9)Eosinophilia and eosinophilic infiltration into splenic B-cell high-grade lymphoma in a dog
(10)A Retrospective Study in 21 Shiba Dogs with Chronic Enteropathy
(11)Myeloma-related disorder with leukemic progression in a cat
(12)Expression of Cell Adhesion Molecules and Doublecortin in Canine Anaplastic Meningiomas
(13)Comparative study of cerebellar degeneration in canine neuroaxonal dystrophy, cerebellar cortical abiotrophy, and neuronal ceroid-lipofuscinosis
(14)Pathological and immunohistochemical features of subdural histiocytic sarcomas in 15 dog
(15) 5-azacytidine, a chemotherapeutic drug, induces TAIL-mediated apoptosis in mouse thymocytes in vitro
(16)Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1
(17)Development of a method to detect viral RNA sequences from cultured cells by combining size fraction and a rapid determination system for viral RNA sequences (RDV)
(18)Bat coronaviruses and experimental infection of bats, the Philippines
(19)Bovine viral diarrhea virus nonstructural protein 5A interacts with NIK and IKKβ-binding protein (NIBP)
(20)Glycoprotein C of equine herpesvirus 4 plays a role in viral binding to cell surface heparan sulfate
(21)Novel betaherpesvirus in bats
(22)Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step
(23)cDNA Cloning and Functional Analysis of Rousettus aegyptiacus “Signal Transducer and Activator of Transcription 1” (STAT1)
(24)Reactivity and prevalence of neutralizing antibodies against Japanese strains of bovine viral diarrhea virus subgenotypes
パーマリンクhttps://agriknowledge.affrc.go.jp/RN/3030166699
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